MyBioSource.com's CLN2 antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The CLN2 antibody was generated using TPP1 as the antigen and it reacts with Human.
Description
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq]